Recombinant Human Azurocidin (C-6His)产品图

Recombinant Human Azurocidin (

C-6His)
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  • ¥832 - 21120
  • Solarbio已认证
  • 北京
  • P00773
  • 2026年08月13日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保质期:

      Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.

    • 保存条件:

      Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.

    • 英文名:

      Azurocidin

    • 库存:

      999

    • 供应商:

      北京索莱宝科技有限公司

    • 规格:

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥832.00
    规格:50ug产品价格:¥2288.00
    规格:500ug产品价格:¥14784.00
    规格:1mg产品价格:¥21120.00
    基因名Azurocidin
    别名Azurocidin; Cationic Antimicrobial Protein CAP37; Heparin-Binding Protein; HBP; AZU1
    蛋白号P20160
    种属Human
    宿主HEK293
    产品描述Recombinant Human Cationic Antimicrobial Protein-37 is produced by our Mammalian expression system and the target gene encoding Ile27-Pro250 is expressed with a 6His tag at the C-terminus.
    区间范围Ile27-Pro250
    标签信息C-6His
    预测分子量38 kDa
    表观分子量38 KDa, reducing conditions
    纯度≥95% by SDS‐PAGE.
    内毒素<1EU/ug as determined by LAL test.
    溶剂Lyophilized from a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, pH 7.5.
    复溶Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml.
    储存条件Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at:
    2-8°C for 2-7 days under sterile conditions after redissolves;
    -20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves;
    -20°C to -70℃ for 12 months in lyophilized state.
    运输条件冷冻运输
    背景说明Azurocidin is an Azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. Azurocidin is a member of the serine protease family that includes Cathepsin G, Neutrophil Elastase (NE), and Proteinase 3 (PR3), however, Azurocidin is not a serine proteinase since the active site serine and histidine residues are replaced. Human Azurocidin together with NE and PR3 are expressed coordinately and are packaged together into azurophil granules during neutrophil differentiation. Azurocidin has been identified as a modulator of endothelial permeability and an important multifunctional inflammatory mediator. Neutrophils arriving first at sites of inflammation release Azurocidin which acts in a paracrine fashion on endothelial cells causing the development of intercellular gaps and allowing leukocyte extravasation. Azurocidin thus be regarded as a reasonable therapeutic target for a variety of inflammatory disease conditions.
    细胞活性No activity experimental data, to be verified.
    ELISA活性No activity experimental data, to be verified.
    SPR/BLI活性No activity experimental data, to be verified.
    研究领域生物制药相关研究
    英文名称Azurocidin
    中文名称Azurocidin蛋白
    单位支
    规格10ug ; 50ug ; 500ug ; 1mg

    Azurocidin 1 inhibits the aberrant proliferation of triple negative breast cancer through the regulation of pyroptosis
    Author:
    Shanshan Lei, Shutong Li, Weiwei Xiao, Qiuping Jiang, Shifan Yan, Wen Xiao, Jiaodi Cai, Jingjing Wang, Lianhong Zou, Fang Chen, Yanjuan Liu, Yu Jiang
    IF:
    4.2000
    Publish_to:
    ONCOLOGY REPORTS
    PMID:
    37681500

    产品细节图片1
    Purity-SDS-PAGE

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