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- Solarbio
- P00773
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2288.0 |
| 规格： | 10ug | 产品价格： | ￥832.0 |
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Azurocidin 1 inhibits the aberrant proliferation of triple negative breast cancer through the regulation of pyroptosis
成员:Shanshan Lei, Shutong Li, Weiwei Xiao, Qiuping Jiang, Shifan Yan, Wen Xiao, Jiaodi Cai, Jingjing Wang, Lianhong Zou, Fang Chen, Yanjuan Liu, Yu Jiang
论文因子:4.2 发表期刊:ONCOLOGY REPORTS pmid:37681500
| 基本信息 | |
| 基因名 | |
| 别名 | Azurocidin;Cationic Antimicrobial Protein CAP37;Heparin-Binding Protein;HBP;AZU1 |
| 中文名称 | Recombinant Human Azurocidin/CAP37/HBP |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, pH 7.5. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Azurocidin is an Azurophil granule antibiotic protein，with monocyte chemotactic and antibacterial activity.The Azurophil granules，specialized lysosomes of the neutrophil，contain at least 10 proteins implicated in the killing of microorganisms.Azurocidin is a member of the serine protease family that includes Cathepsin G，Neutrophil Elastase (NE)，and Proteinase 3 (PR3)，however，Azurocidin is not a serine proteinase since the active site serine and histidine residues are replaced.Human Azurocidin together with NE and PR3 are expressed coordinately and are packaged together into azurophil granules during neutrophil differentiation.Azurocidin has been identified as a modulator of endothelial permeability and an important multifunctional inflammatory mediator.Neutrophils arriving first at sites of inflammation release Azurocidin which acts in a paracrine fashion on endothelial cells causing the development of intercellular gaps and allowing leukocyte extravasation.Azurocidin thus be regarded as a reasonable therapeutic target for a variety of inflammatory disease conditions. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Azurocidin 1 inhibits the aberrant proliferation of triple negative breast cancer through the regulation of pyroptosis
成员:Shanshan Lei, Shutong Li, Weiwei Xiao, Qiuping Jiang, Shifan Yan, Wen Xiao, Jiaodi Cai, Jingjing Wang, Lianhong Zou, Fang Chen, Yanjuan Liu, Yu Jiang
论文因子:4.2 发表期刊:ONCOLOGY REPORTS pmid:37681500
Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
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