P00763 Recombinant Human IFN-a
lpha/beta R1/IFNAR1/Interferon alpha/beta receptor 1/ 细胞因子/蛋白- ￥832 - 21120
- Solarbio
- P00763
- 北京
- 2025年07月25日
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- 库存：
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- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2288.0 |
| 规格： | 10ug | 产品价格： | ￥832.0 |
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Enterovirus D68 3C protease antagonizes type I interferon signaling by cleaving signal transducer and activator of transcription 1
成员:Xiaohan Li, Haoran Guo, Jiaxin Yang, Xize Liu, Huili Li, Wanying Yang, Lili Zhang, Yan Li, Wei Wei
论文因子:5.4 发表期刊:JOURNAL OF VIROLOGY pmid:38240591
| 基本信息 | |
| 基因名 | |
| 别名 | Interferon Alpha/Beta Receptor 1;IFN-R-1;IFN-Alpha/Beta Receptor 1;Cytokine Receptor Class-II Member 1;Cytokine Receptor Family 2 Member 1;CRF2-1;Type I Interferon Receptor 1;IFNAR1;IFNAR |
| 中文名称 | Recombinant Human IFN-alpha/beta R1/IFNAR1/Interferon alpha/beta receptor 1/ |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | The Interferon-α/β Receptor 1 (IFN-α/β R1) is a receptor which binds Type I Interferons including Interferon-α and -β.It is a cell surface receptor and heteromeric receptor composed of one chain with two subunits referred to as IFNAR1 and IFNAR2.IFN-α/β R1，in association with IFN-α/β R2，is required for propagating antiviral signal transduction triggered by IFN-α and IFN-β.IFN-α/β R1 interacts very weakly or not at all with type 1 interferons and does not stably interact with IFN-α/β R2.Ligands associate with IFN-α/β R2，and this complex subsequently forms a stable ternary assembly with IFN-α/β R1.IFN-α/β R1 also associates with IFN-γ R2 even in the absence of IFN-γ stimulation.Human IFN-α/β R1 contains a nuclear localization signal in its extracellular domain that is required for receptor translocation to the nucleus following interaction with ligand.Interferon stimulation results in an immunologic response that is especially associated with viruses. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Enterovirus D68 3C protease antagonizes type I interferon signaling by cleaving signal transducer and activator of transcription 1
成员:Xiaohan Li, Haoran Guo, Jiaxin Yang, Xize Liu, Huili Li, Wanying Yang, Lili Zhang, Yan Li, Wei Wei
论文因子:5.4 发表期刊:JOURNAL OF VIROLOGY pmid:38240591
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