- ￥832 - 22680
- Solarbio
- P00748
- 北京
- 2025年07月25日
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- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥22680.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2275.0 |
| 规格： | 10ug | 产品价格： | ￥832.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | T-cell immunoreceptor with Ig and ITIM domains;;VSIG9;VSTM3;TIGIT;V-set and transmembrane domain-containing protein 3;V-set and immunoglobulin domain-containing protein 9 |
| 中文名称 | Recombinant Human TIGIT/VSIG9/VSTM3 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | T cell immunoreceptor with Ig and ITIM domains (TIGIT) is a member of the CD28 family within the Ig superfamily of proteins.TIGIT is expressed on NK cells and subsets of activated，memory and regulatory T cells，and particularly on follicular helper T cells within secondary lymphoid organs.It binds to CD155 and Nectin-2 that appear on dendritic cells (DC) and endothelium.Ligation of TIGIT on T cells down-regulates TCR-mediated activation and subsequent proliferation，while NK cell TIGIT ligation blocks NK cell cytotoxicity.Through CD155 and Nectin-2，which also interact with DNAM-1/CD226 and CD96/Tactile，TIGIT is part of an interacting network of Ig superfamily members that may augment or oppose each other.In particular，TIGIT binding to CD155 can antagonize the effects of DNAM1. |
| 来源 | Human Cells |
| 溶剂 | Dissolve the lyophilized protein in distilled water. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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