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P00524 Recombinant Human ALK-2

/Activin RIA 细胞因子/蛋白
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  • ¥520 - 10080
  • Solarbio已认证
  • P00524
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥10080.0
    规格:500ug产品价格:¥6240.0
    规格:50ug产品价格:¥1092.0
    规格:10ug产品价格:¥520.0
    基本信息
    基因名
    别名Activin Receptor Type-1;Activin Receptor Type I;ACTR-I;Activin Receptor-Like Kinase 2;ALK-2;Serine/Threonine-Protein Kinase Receptor R1;SKR1;TGF-B Superfamily Receptor Type I;TSR-I;ACVR1;ACVRLK2
    中文名称Recombinant Human ALK-2/Activin RIA
    外观(性状)Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明Activin receptor type-1,also known as Activin receptor type I,Activin receptor-like kinase 2,Serine/threonine-protein kinase receptor R1,TGF-B superfamily receptor type I,ACVRLK2 and ACVR1,is a single-pass type I membrane protein.ACVR1 is expressed in normal parenchymal cells,endothelial cells,fibroblasts and tumor-derived epithelial cells.ACVR1 belongs to the protein kinase superfamily.Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors.These receptors are all transmembrane proteins,composed of a ligand-binding extracellular domain with cysteine-rich region,a transmembrane domain,and a cytoplasmic domain with predicted serine/threonine specificity.Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors.Type I and II receptors form a stable complex after ligand binding,resulting in phosphorylation of type I receptors by type II receptors.ACVR1 signals a particular transcriptional response in concert with activin type II receptors.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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