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- Solarbio
- P00523
- 北京
- 2025年07月25日
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- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥10080.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥6240.0 |
| 规格： | 50ug | 产品价格： | ￥1092.0 |
| 规格： | 10ug | 产品价格： | ￥520.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Activin Receptor Type-1B;Activin Receptor Type IB;ACTR-IB;Activin Receptor-Like Kinase 4;ALK-4;Serine/Threonine-Protein Kinase Receptor R2;SKR2;ACVR1B;ACVRLK4;ALK4 |
| 中文名称 | Recombinant Human ALK-4/Activin RIB/Activin Receptor IB/ACVR1B |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Activin Receptor Type-1B (ACVR1B) is a single-pass type I membrane protein that belongs to the protein kinase superfamily.ACVR1B contains one GS domain and one protein kinase domain and is expressed in many tissues，most strongly in kidney，pancreas，brain，lung，and liver.ACVR1B acts as a transducer of activin or activin like ligands signals.Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B，ACVR2A or ACVR2B activating ACVR1B through phosphorylation of its regulatory GS domain.They go on to recruit the R-SMADs，SMAD2 and SMAD3.ACVR1B also transducers signals of nodal，GDF-1，and Vg1.Mutations in ACVR1B are associated with pituitary tumors. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验In this chapter we describe efficient procedures for the construction, expression and screening of comprehensive libraries of human Fab antibody fragments displayed on the surface of filamentous phage. Phagemid vectors are used for placing
a look from the following website just by clicking "Tyrosine Phosphorylation and Dimerization" http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WSN-43F85YV-2&_user=1111158&_coverDate=06%2F29%2F2001&_rdoc=1&_fmt=full&_orig=search
Overview of Receptor Allosterism
Figure 1.21.2 Effect of: (A ) negative allosteric modulator, (B ) positive allosteric modulator, or (C ) a competitive antagonist on orthosteric ligand‐receptor occupancy (ρA ). For all the simulations, p K
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