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P00478 Recombinant Human HB-EG

F/proHB-EGF/Heparin Binding EGF like Growth Factor 细胞因子/蛋白
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  • ¥520 - 7920
  • Solarbio已认证
  • P00478
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥7920.0
    规格:500ug产品价格:¥5980.0
    规格:50ug产品价格:¥1196.0
    规格:10ug产品价格:¥520.0
    基本信息
    基因名
    别名Diphtheria toxin receptor;DTR;HEGFL;heparin-binding EGF-like growth factor;DTS;DTSF;heparin-binding epidermal growth factor;proheparin-binding EGF-like growth factor;HB-EGF;pro HB-EGF
    中文名称Recombinant Human HB-EGF/proHB-EGF/Heparin Binding EGF like Growth Factor
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明Heparin-binding EGF-like growth factor (HB-EGF) is a 12-16 kDa member of the epidermal growth factor (EGF) family.It possesses an EGF-like domain,and a heparin-binding motif.Mature HB-EGF is a soluble peptide that arises from proteolytic processing of the transmembrane form.Human HB-EGF shows 76% and 73% aa sequence identity with rat and mouse HB-EGF,respectively.It is required for normal cardiac valve formation and normal heart function,promotes smooth muscle cell proliferation.It may be involved in macrophage-mediated cellular proliferation; it is mitogenic for fibroblasts,but not endothelial cells.HB-EGF classified as a group 2 ErbB ligand based on its ability to activate both the EGF/ErbB1 and ErbB4 receptors.Activity associated with ErbB4 binding appears to be limited to non-mitogenic actions,while EGFR binding induces both mitogenic and non-mitogenic activity.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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    P00478 Recombinant Human HB-EGF/proHB-EGF/Heparin Binding EGF like Growth Factor 细胞因子/蛋白
    ¥520 - 7920