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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥19200.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥13440.0 |
| 规格: | 50ug | 产品价格: | ¥1778.0 |
| 规格: | 10ug | 产品价格: | ¥593.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | T-lymphocyte activation antigen CD80;Activation B7-1 antigen;B7;CD80 |
| 中文名称 | Recombinant Cynomolgus B7-1/CD80/T-lymphocyte Activation Antigen CD80 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH 7.5. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Cynomologous Cluster of Differentiation 80,also called B7-1,is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells,macrophages and dendritic cells.CD80 plays key,yet distinct roles in the activation of T cells.B7-1/CD80 and B7-2/CD86,together with their receptors CD28 and CTLA4,constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses.CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells,macrophages and dendritic cells.Although both CTLA-4 and CD28 can bind to the same ligands,CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response.CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas. |
| 来源 | Human Cells |
| 溶剂 | Dissolve the lyophilized protein in distilled water. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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