P00539 Recombinant Cynomolgus B7-1/CD80/T-lymphocyte Activation Antigen CD80 细胞因子/蛋白

P00539 Recombinant Cynomolgus

B7-1/CD80/T-lymphocyte Activation Antigen CD80 细胞因子/蛋白
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  • ¥593 - 19200
  • Solarbio已认证
  • P00539
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥19200.0
    规格:500ug产品价格:¥13440.0
    规格:50ug产品价格:¥1778.0
    规格:10ug产品价格:¥593.0
    基本信息
    基因名
    别名T-lymphocyte activation antigen CD80;Activation B7-1 antigen;B7;CD80
    中文名称Recombinant Cynomolgus B7-1/CD80/T-lymphocyte Activation Antigen CD80
    外观(性状)Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH 7.5.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明Cynomologous Cluster of Differentiation 80,also called B7-1,is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells,macrophages and dendritic cells.CD80 plays key,yet distinct roles in the activation of T cells.B7-1/CD80 and B7-2/CD86,together with their receptors CD28 and CTLA4,constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses.CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells,macrophages and dendritic cells.Although both CTLA-4 and CD28 can bind to the same ligands,CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response.CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas.
    来源Human Cells
    溶剂Dissolve the lyophilized protein in distilled water.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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