- ￥312 - 9120
- Solarbio
- P00338
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥9120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥6240.0 |
| 规格： | 50ug | 产品价格： | ￥936.0 |
| 规格： | 10ug | 产品价格： | ￥312.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Ubiquitin-Conjugating Enzyme E2 K;Huntingtin-Interacting Protein 2;HIP-2;Ubiquitin Carrier Protein;Ubiquitin-Conjugating Enzyme E2-25 kDa;Ubiquitin-Conjugating Enzyme E2(25K);Ubiquitin-Conjugating Enzyme E2-25K;Ubiquitin-Protein Ligase;UBE2K;HIP2;LIG |
| 中文名称 | Recombinant Human UBE2K/Ubiquitin-conjugating enzyme E2 K |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Ubiquitin-Conjugating Enzyme E2 K (UBE2K) belongs to the E2 Ubiquitin-Conjugating Enzyme family.UBE2K is highly expressed in the brain，with highest levels found in cortex and striatum，and at lower levels in cerebellum and brainstem.UBE2K may mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53.UBE2K is associated with the selective degradation of short-lived and abnormal proteins，such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins.In addition，UBE2K is involved in Alzheimer's disease，Huntington's disease and antigen processing through its interaction with huntingtin，and MHC-heavy chain proteins. |
| 来源 | E.coli |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验Studies of the Ubiquitin Proteasome System
in Insect Cells Using a Baculovirus System Alternate Protocol 11: Preparation of Rabbit E1 Support Protocol 4: Generation of Empty Bacterial Lysates Generation of Ubiquitin‐Conjugating Enzymes (E2s) Basic Protocol 22: Expression of E2s in E. coli
Proteasomes that Lack Endogenous USP14 and are Devoid of UB‐AMC Hydrolysis Activity Support Protocol 2: Purification of Recombinant Human USP14 from E. coli Support Protocol 3: Synthesis and Purification of Ubiquitin
P is the catalytic subunit of the enzyme. Cell. 1983, 35 (3 Pt 2): 849-57. PMID 6197186. ^ (英文)1989年度诺贝尔化学奖 ^ 3.0 3.1 (英文)Jarrous N, Reiner R. Human RNase P: a tRNA-processing enzyme and transcription factor. Nucleic Acids Res.. 2007, 35
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