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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥2912.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥2038.0 |
| 规格: | 50ug | 产品价格: | ¥312.0 |
| 规格: | 10ug | 产品价格: | ¥104.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Small Ubiquitin-Related Modifier 1;SUMO-1;GAP-Modifying Protein 1;GMP1;SMT3 Homolog 3;Sentrin;Ubiquitin-Homology Domain Protein PIC1;Ubiquitin-Like Protein SMT3C;Smt3C;Ubiquitin-Like Protein UBL1;SUMO1;SMT3C;SMT3H3;UBL1 |
| 中文名称 | Recombinant Human SUMO1/Small ubiquitin-related modifier 1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 50mM TrisHCl, 100mM NaCl, 1mM DTT, pH 8.5 . |
| 纯度 | ≥90% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Small Ubiquitin-Related Modifier 1 (SUMO1) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily.It is a family of small,related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation.SUMO1 functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system.This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport,DNA replication and repair,mitosis and signal transduction.SUMO1 is involved in a variety of cellular processes,such as nuclear transport,transcriptional regulation,apoptosis,and protein stability.SUMO1 is not active until the last four amino acids of the carboxy-terminus are cleaved off.Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins and may also regulate a network of genes involved in palate development. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验Studies of the Ubiquitin Proteasome System
both in vitro and in cells. Because another protein modifier, NEDD8, itself regulates aspects of the ubiquitin system, basic protocols on neddylation are also included in this unit. Keywords: Ubiquitin; ubiquitylation; proteasomal degradation; protein
Preparation of Recombinant Protein Spotted Arrays for Proteome‐Wide Identification of Kinase Targets
, H. 2009. Profiling the human protein‐DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling. Cell 139:610‐622. Hudson, J.R., Jr., Dawson, E.P
Introduction of human 14-3-3 proteins
protein revealed that the neuron-specific 14-3-3-related proteins are highly conserved (60-88%)throughout eukaryotic evolution.--------------------------------------------------------------------------------The human and bovine 14-3-3 eta protein mRNAs
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