Recombinant Human KRAS (G12V, N-6His)产品图

Recombinant Human KRAS (G12V,

N-6His)
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  • ¥442 - 9180
  • Solarbio已认证
  • 北京
  • P00403
  • 2026年08月13日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保质期:

      Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.

    • 保存条件:

      Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.

    • 英文名:

      KRAS

    • 库存:

      999

    • 供应商:

      北京索莱宝科技有限公司

    • 规格:

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥442.00
    规格:50ug产品价格:¥1326.00
    规格:500ug产品价格:¥6120.00
    规格:1mg产品价格:¥9180.00
    基因名KRAS
    别名Ki-Ras; c-K-ras; KRAS2; RASK2; CFC2
    蛋白号AAH13572.1
    种属Human
    宿主E.coli
    产品描述Recombinant Human GTPase Kras is produced by our E.coli expression system and the target gene encoding Thr2-Cys185(Gly12Val) is expressed with a 6His tag at the N-terminus.
    区间范围Thr2-Cys185(G12V)
    标签信息N-6His
    预测分子量25-30 kDa
    表观分子量25-30 KDa, reducing conditions
    纯度≥95% by SDS‐PAGE.
    内毒素<1EU/ug as determined by LAL test.
    溶剂Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    复溶Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml.
    储存条件Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at:
    2-8°C for 2-7 days under sterile conditions after redissolves;
    -20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves;
    -20°C to -70℃ for 12 months in lyophilized state.
    运输条件冷冻运输
    背景说明K-Ras belongs to the small GTPase superfamily, Ras family. As other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. K-Ras functions as a molecular on/off switch. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner. Besides essential function in normal tissue signaling, the mutation of a K-Ras gene is an essential step in the development of many cancers. Several germline K-Ras mutations have been found to be associated with Noonan syndrome[4] and cardio-facio-cutaneous syndrome. Somatic K-Ras mutations are found at high rates in Leukemias, colon cancer, pancreatic cancer and lung cancer.
    细胞活性No activity experimental data, to be verified.
    ELISA活性No activity experimental data, to be verified.
    SPR/BLI活性No activity experimental data, to be verified.
    研究领域生物制药相关研究
    英文名称KRAS
    中文名称KRAS蛋白
    单位支
    规格10ug ; 50ug ; 500ug ; 1mg

    产品细节图片1
    Purity-SDS-PAGE

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