IB0490 苯甲酸 抗感染 索莱宝

Benzoic Acid 具有抗菌活性，常作为防腐剂中的一种有效成分。

使用本产品的应用案例（仅供参考）

In Vivo

Rat（Sprague-Dawley rats (male,200 ± 20 g) ，20 mg/kg benzoic acid， 口服）

A positive drug (indomethacin, 20 mg/kg) and a non-positive drug (benzoic acid, 20 mg/kg) were mixed (1:1) and orally administered to the 6 different rats. The other experimental conditions and methods are the same as those discussed in 2.4.1.

来源文献：Gegentana, Xu F, Li FC, Zhang YF, Shen SJ, Yang P, Yang XX, Shang MY, Liu GX, Li YL, XuanWang, Cai SQ. Discovery of the active compounds of Smilacis Glabrae Rhizoma by utilizing the relationship between the individual differences in blood drug concentration and the pharmacological effect in rats. J Ethnopharmacol. 2020 Aug 10;258:112886. doi: 10.1016/j.jep.2020.112886. Epub 2020 Apr 21. PMID: 32325179.

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标题:Modulating Whey Proteins Antigenicity with Lactobacillus delbrueckii subsp. bulgaricus DLPU F-36 Metabolites: Insights from Spectroscopic and Molecular Docking Studies

成员:Zhao Zhang, YunPeng Xu, Xinling Li, Lei Chi, Yue Li, Chao Xu, Guangqing Mu, Xuemei Zhu

论文因子:5.7 发表期刊:JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY pmid:38941263

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标题:Characterization of differences in physicochemical properties, volatile organic compounds and non-volatile metabolites of prune wine by inoculation of different lactic acid bacteria during malolactic fermentation

成员:Jianqiao Jiang, Yun Xie, Miao Cui, Xiaomei Ma, Ruonan Yin, Yiwen Chen, Yongkang Li, Yue Hu, Weidong Cheng, Feifei Gao

论文因子:8.5 发表期刊:FOOD CHEMISTRY pmid:38759436

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标题:Gut microbiota-based metabolites of Xiaoyao Pills (a typical Traditional Chinese medicine) ameliorate depression by inhibiting fatty acid amide hydrolase levels in brain

成员:Zheng-Wei Zhang, Pei Han, Jie Fu, Hang Yu, Hui Xu, Jia-Chun Hu, Jin-Yue Lu, Xin-Yu Yang, Hao-Jian Zhang, Meng-Meng Bu, Jian-Dong Jiang, Yan Wang

论文因子:5.195 发表期刊:JOURNAL OF ETHNOPHARMACOLOGY pmid:37100263

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标题:Salidroside pretreatment protects against myocardial injury induced by heat stroke in mice

成员:Chen GD; Fan H; Zhu JH

论文因子:1.573 发表期刊:J Int Med Res pmid:31448659

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标题:Discovery of the active compounds of Smilacis Glabrae Rhizoma by utilizing the relationship between the individual differences in blood drug concentration and the pharmacological effect in rats

成员:Gegentana;XuF;LiFC;ZhangYF;ShenSJ;YangP;YangXX;Sha

论文因子:4.275 发表期刊:J Ethnopharmacol pmid:32325179

基本信息
CAS	No.65-85-0
中文名称	苯甲酸
英文名称	Benzoic acid
别名	FEMA 2131;Dracylic acid;安息香酸
分子式	C6H5COOH
分子量	122.12
溶解性	Soluble in DMSO
纯度	GC≥99%
外观(性状)	White to off-white Solid
储存条件	Powder:2-8℃，2 years;Insolvent(母液):-20℃，6 months;-80℃，1 year
EC	EINECS 200-618-2
MDL	MFCD00002398
SMILES	O=C(O)C1=CC=CC=C1
InChIKey	WPYMKLBDIGXBTP-UHFFFAOYSA-N
InChI	InChI=1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)
PubChem CID	243
靶点	Bacterial
通路	Anti-infection
背景说明	Benzoic Acid 具有抗菌活性,常作为防腐剂中的一种有效成分。
生物活性	Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi.[1]
数据来源文献	[1]. Nair B， et al. Final report on the safety assessment of Benzyl Alcohol， Benzoic Acid， and Sodium Benzoate. Int J Toxicol. 2001;20 Suppl 3:23-50.
单位	瓶