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- 2025年07月23日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder:2-8℃，2 years;Insolvent(母液):-20℃，6 months;-80℃，1 year
- 保质期：
Powder:2-8℃，2 years;Insolvent(母液):-20℃，6 months;-80℃，1 year
- 英文名：
L-Alanyl-L-glutamine
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- CAS号：
39537-23-0
- 规格：
100mg
使用本产品的案例（仅供参考）
In Vivo
Mice（early weaning mice；2% L-alanyl-L-glutamine；饮水；7天）
To investigate the effects of Gln supplementation on early weaning mice, early weaning pups from the same litter were randomly divided into two groups on the basis of similar body weights (n = 3–4 per group). Mice in the weaned group were free to drink water, while the Ala-Gln group was free to drink 2% L-alanyl-L-glutamine (Solarbio, Beijing, China) supplemented water, equaling a solution of 111 mM Ala-Gln. To assess the effects of alanine (Solarbio) supplementation on early weaning mice, early weaning pups from the same litter were randomly divided into two groups on the basis of similar body weights (n = 3–4 per group). The weaned group was free to drink water, while the Ala group was free to drink a solution of 111 mM of L-alanine (Solarbio) in water. Three or more weaning mice were caged together in each group. We measured the body weight every day and recorded food consumption weekly in the groups. The water was changed every 3 days. On day 7 post-weaning, the mice were sacrificed to collect jejunual tissues and blood for further analysis.
来源文献：Tian J, Li Y, Bao X, Yang F, Tang X, Jiang Q, Yang C, Yin Y, Yao K. Glutamine boosts intestinal stem cell-mediated small intestinal epithelial development during early weaning: Involvement of WNT signaling. Stem Cell Reports. 2023 Jul 11;18(7):1451-1467. doi: 10.1016/j.stemcr.2023.05.012. Epub 2023 Jun 15. PMID: 37327782.
Mice（111 mM of L-alanine）
The weaned group was free to drink water, while the Ala group was free to drink a solution of 111 mM of L-alanine (Solarbio) in water.
文献来源：Tian J, Li Y, Bao X, Yang F, Tang X, Jiang Q, Yang C, Yin Y, Yao K. Glutamine boosts intestinal stem cell-mediated small intestinal epithelial development during early weaning: Involvement of WNT signaling. Stem Cell Reports. 2023 Jul 11;18(7):1451-1467. doi: 10.1016/j.stemcr.2023.05.012. Epub 2023 Jun 15. PMID: 37327782; PMCID: PMC10362502.
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Glutamine boosts intestinal stem cell-mediated small intestinal epithelial development during early weaning: Involvement of WNT signaling
成员:Tian J; Li Y; Bao X; Yang F; Tang X; Jiang Q; Yang
论文因子:5.9 发表期刊:Stem Cell Reports pmid:37327782
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
| 基本信息 | |
| CAS | No.39537-23-0 |
| 中文名称 | L-丙氨酸-L-谷氨酰胺 |
| 英文名称 | L-Alanyl-L-glutamine |
| 分子式 | C8H15N3O4 |
| 分子量 | 217.22 |
| 溶解性 | Soluble in Water ≥5mg/mL(Need ultrasonic) |
| 纯度 | ≥98% |
| 外观(性状) | White to off-white Solid |
| 储存条件 | Powder:2-8℃，2 years;Insolvent(母液):-20℃，6 months;-80℃，1 year |
| EC | EINECS 475-290-9 |
| MDL | MFCD00133046 |
| SMILES | CC(C(=O)NC(CCC(=O)N)C(=O)O)N |
| InChIKey | HJCMDXDYPOUFDY-WHFBIAKZSA-N |
| InChI | InChI=1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H，2-3，9H2，1H3，(H2，10，12)(H，11，13)(H，14，15)/t4-，5-/m0/s1 |
| PubChem CID | 123935 |
| 靶点 | Others |
| 通路 | Others |
| 背景说明 | L-Alanyl-L-glutamine 是一种二肽，具有多种重要的生物活性，也是L-glutamine的可替代添加剂，具有良好的溶解性和稳定性。 |
| 单位 | 瓶 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Glutamine boosts intestinal stem cell-mediated small intestinal epithelial development during early weaning: Involvement of WNT signaling
成员:Tian J; Li Y; Bao X; Yang F; Tang X; Jiang Q; Yang
论文因子:5.9 发表期刊:Stem Cell Reports pmid:37327782
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
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