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- 2025年07月21日
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文献和实验Evaluating Amyloid Beta (A) 1-40 Degradation by Capillary Electrophoresis
Here, we describe a capillary electrophoresis method for evaluating proteolysis of the amyloid beta peptide (Aβ) 1–40. This method is suitable for kinetic studies, demands little specialized equipment, and consumes only small
α-Synuclein/Amyloid Interactions
Human α-synuclein was originally identified as the precursor of a peptide named non-Aβ component of Alzheimer’s disease (NAC) that was tightly associated to purified Alzheimer’s disease amyloid (1 ). Senile amyloid plaques consist predominantly
Interaction of the Presenilins with the Amyloid Precursor Protein (APP)
the deposition of amyloid Aβ peptide. The latter is released from its cognate amyloid precursor protein (APP) by a two-step proteolytic conversion: first, proteolysis of APP by β-secretase, which releases the N-terminus of Aβ, and second, conversion
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