Quercetin 3-O-β-D-xylopyranosi

一种具有多种生物活性的黄酮类糖苷；在浓度为10µg/ml时可降低大鼠离体脑中的MDA水平；在浓度为10、50和100µg/ml时可降低AR42J大鼠胰腺腺泡细胞胰腺炎模型中LPS和cerulein诱导的ROS生成和GRP78水平的增加；在浓度为12.5、25和50mg/kg时可降低大鼠缺血性心力衰竭模型中的血清TNF-α和IL-6水平、心肌MDA水平和心肌纤维化，并改善心脏功能。A flavonoid glycoside with diverse biological activities; reduces MDA levels in isolated rat brain at 10 µg/ml; reduces LPS- and cerulein-induced increases in ROS production and levels of GRP78 in an AR42J rat pancreatic acinar cell model of pancreatitis at 10, 50, and 100 µg/ml; decreases serum TNF-α and IL-6 levels, myocardial MDA levels, and myocardial fibrosis, as well as improves cardiac function, in a rat model of ischemic heart failure at 12.5, 25, and 50 mg/kg.分子式C20H18O11分子量434.4O=C(C(O[C@H]1[C@@H]([C@H]([C@@H](CO1)O)O)O)=C(C2=CC(O)=C(O)C=C2)OC3=CC(O)=C4)C3=C4O