Luteolin 7-O-Rutinoside

一种具有多种生物活性的黄酮类糖苷；在无细胞测定中可清除1-50µM的DPPH自由基；对多种细菌有效（MIC=100-200µg/ml）；对白色念珠菌、酿酒酵母和葡萄牙念珠菌有效（MIC分别为100、200和50µg/ml）；在57.6µg/只动物的多磷酸盐诱发的致死性内毒血症小鼠模型中，可减轻肝肾损伤并提高存活率。A flavonoid glycoside with diverse biological activities; scavenges DPPH radicals in a cell-free assay from 1-50 µM; active against various bacteria (MICs = 100-200 µg/ml); active against C. albicans, S. cerevisiae, and C. lusitaniae (MICs = 100, 200, and 50 µg/ml, respectively); decreases hepatic and renal injury and increases survival in a mouse model of polyphosphate-induced lethal endotoxemia at 57.6 µg/animal.分子式C27H30O15分子量594.5O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O)C=C2OC(C5=CC(O)=C(C=C5)O)=C1