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质子泵抑制剂（猪胃膜囊泡中的IC50=0.53µM）；以10mg/kg的剂量抑制幽门结扎大鼠的基础胃酸分泌；降低反流性食管炎大鼠模型的食管黏膜组织MPO水平（ED50=5.9mg/kg）；减少萘普生、WIRS或乙醇诱发的胃溃疡大鼠模型的溃疡面积（ED50s分别为0.1、0.1和1.4mg/kg）。A proton pump inhibitor (IC50 = 0.53 µM in porcine gastric membrane vesicles); inhibits basal gastric acid secretion in pylorus-ligated rats at 10 mg/kg; reduces esophageal mucosal tissue MPO levels in a rat model of reflux esophagitis (ED50 = 5.9 mg/kg); reduces ulcer area in rat models of naproxen-, WIRS-, or ethanol-induced gastric ulcers (ED50s = 0.1, 0.1, and 1.4 mg/kg, respectively).分子式C20H19F2N3O3分子量387.4CN(C)C(C1=CC(O[C@@H]2C3=C(F)C=C(F)C=C3OCC2)=C4C(N=C(N4)C)=C1)=O