Creatinine

肌酸-磷酸肌酸能量交换的最终产物；由肌酸的自发和非酶促环化以及通过磷酸肌酸通过磷酸肌酸酐中间体在骨骼肌和脑中形成；在小鼠运动后的尿液中以及在喂食高蛋白饮食20个月的大鼠的血浆中增加；血清肌酐水平已用于估计GFR和作为肾功能障碍的标志。The end product of the creatine-creatine phosphate energy shuttle; formed by the spontaneous and non-enzymatic cyclization of creatine, as well as from creatine phosphate via a phosphorylcreatinine intermediate, in skeletal muscle and brain; increased in the urine after exercise in mice and in the plasma of rats fed a high-protein diet for 20 months; serum creatinine levels have been used to estimate the GFR and as a marker of renal dysfunction.分子式C4H7N3O分子量113.1O=C1CN(C)C(N)=N1