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文献和实验Microarrays for the Study of Viral Gene Expression During Human Cytomegalovirus Latent Infection
Human cytomegalovirus (HCMV) is one of the largest known DNA viruses. It is ubiquitous, and following resolution of primary productive infection, it persists in the human host by establishing a lifelong latent infection in myeloid lineage cells
Cytomegalovirus latency depends on an interaction with hematopoietic cells in bone marrow and peripheral blood. The distribution of latent viral DNA and transcripts in these cells was investigated using methods based on polymerase chain
Antibodies for Detecting EBV Latent Proteins
studies, which implicated EBV as a factor in various diseases ( 1 – 4 ). However, human sera also contain antibodies to EBV latent gene products, as first demonstrated in an immunofluorescence test that detected predominantly EBNA1 (
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