IA2690 5-氨基乙酰PPA盐酸盐 抑制剂/拮抗剂/激动剂 索莱宝产品图
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IA2690 5-氨基乙酰PPA盐酸盐 抑制剂/拮抗剂/激动

剂 索莱宝
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  • ¥220 - 540
  • Solarbio已认证
  • 北京
  • IA2690
  • 2026年05月21日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Powder:2-8℃,2 years;Insolvent(母液):-20℃,6 months;-80℃,1 year

    • 保质期

      Powder:2-8℃,2 years;Insolvent(母液):-20℃,6 months;-80℃,1 year

    • 英文名

      5-Aminolevulinic Acid Hydrochloride

    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • CAS号

      5451-09-2

    • 规格

      100mg/50mg/20mg

    规格:100mg产品价格:¥540.0
    规格:50mg产品价格:¥420.0
    规格:20mg产品价格:¥220.0

    是一种化合物,具有生物或化学活性。

    【本资料源自公开渠道,如需(此处)屏蔽,请联系删除】

    标题:Engineering a probiotic strain of Escherichia coli to induce the regression of colorectal cancer through production of 5-aminolevulinic acid

    成员:Junhao Chen, Xiaohong Li, Yumei Liu, Tianyuan Su, Changsen Lin, Lijun Shao, Lanhua Li, Wanwei Li, Guoyu Niu, Jing Yu, Ling Liu, Miaomiao Li, Xiaoli Yu, Qian Wang

    论文因子:5.813 发表期刊:Microbial Biotechnology pmid:34272828

    基本信息
    CASNo.5451-09-2
    中文名称5-氨基乙酰PPA盐酸盐
    英文名称5-Aminolevulinic Acid Hydrochloride
    别名氨基酮戊酸;5-ALA;Hydrangin;ALA hydrochloride;δ-Aminolevulinic acid hydrochloride;5-Amino-4-oxopentanoic acid hydrochloride
    分子式C5H9NO3·HCl
    分子量167.59
    溶解性Soluble in Water ≥25mg/mL
    纯度≥98%
    外观(性状)White to off-white Solid
    储存条件Powder:2-8℃,2 years;Insolvent(母液):-20℃,6 months;-80℃,1 year
    ECEINECS 226-679-5
    MDLMFCD00012869
    SMILESO=C(O)CCC(CN)=O.[H]Cl
    靶点Others
    通路Others
    背景说明5-Aminolevulinic Acid Hydrochloride是一种化合物,具有生物或化学活性。
    生物活性5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles. 5-Aminolevulinic acid hydrochloride (ALA) is a non-fluorescent prodrug that leads to intracellular accumulation of fluorescent porphyrins in malignant gliomas-a finding that is under investigation for intraoperative identification and resection of these tumours. [1-2]
    In VitroMedian follow-up was 35.4 months(95% CI 1.0-56.7). Contrast-enhancing tumour was resected completely in 90(65%)of 139 patients assigned 5-aminolevulinic acid compared with 47(36%)of 131 assigned white light(difference between groups 29% [95% CI 17-40],p<0.0001). Patients allocated 5-aminolevulinic acid had higher 6-month progression free survival than did those allocated white light(41.0% [32.8-49.2] vs 21.1% [14.0-28.2]; difference between groups 19.9% [9.1-30.7],p=0.0003,Z test)[1]. 5-ALA alone proved to be insufficient in attaining gross total resection without the danger of incurring postoperative neurological deterioration. Furthermore,in the case of functional grade III gliomas,iMRI in combination with functional neuronavigation was significantly superior to the 5-ALA resection technique[2] .
    数据来源文献[1]. Stummer, W., et al., Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol, 2006. 7(5): p. 392-401.
    [2]. Eyupoglu, I.Y., et al., Improving the extent of malignant glioma resection by dual intraoperative visualization approach. PLoS One, 2012. 7(9): p. e44885.
    单位

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    图标文献和实验
    该产品被引用文献

    【本资料源自公开渠道,如需(此处)屏蔽,请联系删除】

    标题:Engineering a probiotic strain of Escherichia coli to induce the regression of colorectal cancer through production of 5-aminolevulinic acid

    成员:Junhao Chen, Xiaohong Li, Yumei Liu, Tianyuan Su, Changsen Lin, Lijun Shao, Lanhua Li, Wanwei Li, Guoyu Niu, Jing Yu, Ling Liu, Miaomiao Li, Xiaoli Yu, Qian Wang

    论文因子:5.813 发表期刊:Microbial Biotechnology pmid:34272828

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    • 常用生化试剂

      EDTA,2Na,2H2 O  (乙二胺四乙酸) 100g 90 Amresco分装 B1099 EGTA  乙二醇-双-(2-氨基乙基)-四乙酸 5g/10g 100/160 Amresco分装 B1102  Ficoll 400  (聚蔗糖

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    IA2690 5-氨基乙酰PPA盐酸盐 抑制剂/拮抗剂/激动剂 索莱宝
    ¥220 - 540