Boc-2,5-difluoro-D-phenylalani

Incorporation of Phosphotyrosyl Mimetic 4- (Phosphonodifluoromethyl)phenylalanine (F2Pmp) Into Signal Transduction-Directed Peptides

-stable pTyr mimetics have been developed that retain certain of the chemical and pharmacological properties of pTyr itself. Among these, difluoro-phosphonomethyl phenylalanine (F2 Pmp) has shown widespread utility in a variety of signal transduction

Synthesis and Use of Pseudopeptides Derived from 1,2,4-Oxadiazole-, 1,3,4-Oxadiazole-, and 1,2,4-Triazole-based Dipeptidomimetics

ring (1 ) and one series with a methylene group inserted between the ring and the carboxylic acid group (7 ). Since we have focused on the design and synthesis of Phe-Gly mimetics, the synthetic examples described here start from l -phenylalanine

Enzymes Acting on d-Amino Acid Containing Peptides

aminopeptidase and endopeptidase activities. The enzyme was active toward (d -Phe) n , Boc-(d -Phe) n , (d -Phe) n methyl ester, d -Phe-NH2 , Boc-(d -Phe) n methyl ester, and Boc-(d -Phe) n tert -butyl ester, but not toward (d -Ala) n (n = 2–4), (d