- ￥2260
- LSM Bio
- 进口
- PAab10034
- 2025年07月15日
- ELISA, WB, IHC
- E. coli - derived recombinant protein
- Human, Mouse, Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
chemokine(C-X3-C motif) receptor 1
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse, Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA, WB, IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
chemokine(C-X3-C motif) receptor 1
- 抗体英文名：
CX3CR1 antibody
- 抗体名：
CX3CR1 antibody
- 规格：
100μl
CX3CR1 antibody
Product Name CX3CR1 antibody
Catalog No PAab10034
Packing 100ul
Form liquid
Alternative Name CMKBRL1, GPR13
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Receptor for the CX3C chemokine fractalkine(CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions(PubMed:9390561, PubMed:23125415). Acts as coreceptor with CD4 for HIV-1 virus envelope protein(in vitro)(PubMed:9726990). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1(PubMed:14607932).
Immunogen chemokine(C-X3-C motif) receptor 1
Specificity Human, Mouse, Rat
Tested Application ELISA, WB, IHC
Recommended dilution WB: 1:500-1:2000; IHC: 1:20-1:200
IHC use Immunohistochemistry of paraffin-embedded human colon cancer using PAab10034(CX3CR1 antibody) at dilution of 1:100
WB use
rat brain were subjected to SDS PAGE followed by western blot with PAab10034(CX3CR1 antibody) at dilution of 1:1000
Protein Information
Gene ID 1524
Uniprot ID P49238
Calculated MW 50 kDa
Research Area Neuroscience, Stem Cells, Immunology, Signal Transduction
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文献和实验Analyses of Microglia Effector Function Using CX3CR1-GFP Knock-In Mice
are often used to distinguish the intrinsic versus extrinsic effects of specific mutations. In our case, chimeras help us to better understand the role of CX3CR1 in microglia and peripheral myeloid cells. To detect cell autonomous effects on myeloid cell
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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