- ￥2260
- LSM Bio
- 进口
- PAab09816
- 2025年07月14日
- ELISA, WB, IHC, IF
- E. coli - derived recombinant protein
- Human, Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Phospho-CHEK1-S280
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA, WB, IHC, IF
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
Phospho-CHEK1-S280
- 抗体英文名：
Phospho-CHEK1-S280 antibody
- 抗体名：
Phospho-CHEK1-S280 antibody
- 规格：
100μl
Phospho-CHEK1-S280 antibody
Product Name Phospho-CHEK1-S280 antibody
Catalog No PAab09816
Packing 100ul
Form liquid
Alternative Name CHK1
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
Immunogen Phospho-CHEK1-S280
Specificity Human, Mouse
Tested Application ELISA, WB, IHC, IF
Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
IHC use Immunofluorescence analysis of MCF-7 cells using PAab09816. Blue: DAPI for nuclear staining.
WB use
HT-29 cells were subjected to SDS PAGE followed by western blot with PAab09816 at dilution of 1:1000
Protein Information
Gene ID 1111
Uniprot ID O14757
Calculated MW 60 kDa
Research Area
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文献和实验
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