新型钙离子荧光探针Calbryte 520,钾盐

产品基本信息

产品名称：新型钙离子荧光探针Calbryte 520,钾盐

储存条件：-15℃避光防潮

保质期：12个月

 

产品物理化学光谱特性

分子量：909.02

溶剂：水

激发波长（nm）：492

发射波长（nm）：514

 

产品介绍

新型钙离子荧光探针Calbryte 520,钾盐是美国AAT Bioquest生产的钙离子荧光探针，钙的测量对于许多生物学研究至关重要。荧光探针显示结合钙的光谱响应，使研究人员能够通过荧光显微镜，流式细胞仪，荧光光谱和荧光酶标仪研究细胞游离钙浓度的变化。随后于1989年推出Fluo-3，后来开发出Fluo-4，Fluo-8和Cal-520，具有改进的信号/信号比。但是，Fluo-4仍存在一些严重问题。例如，对于Fluo-3，在使用Fluo-4的所有细胞内钙测定中，需要使用丙磺舒以防止细胞负载的Fluo-4从细胞中泄漏。探针与基于Fluo-4的钙测定法的使用损害了测定结果，因为丙磺舒被证实具有多种复杂的细胞效应。 Calbryte 520是用于钙测量的新一代荧光指示剂，其大大提高的信噪比和更好的细胞内保留特性使CalBryte 520成为强大的钙指示剂。它具有与Fluo-4相同的激发和发射波长，因此相同的Fluo-4测定设置可以容易地应用于基于Calbryte 520的钙测定。，为您提供优质的新型钙离子荧光探针Calbryte 520,钾盐。 

钙离子篇：时间轴式讲解应用于钙离子检测的探针

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参考文献

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Propofol and remifentanil at moderate and high concentrations affect proliferation and differentiation of neural stem/progenitor cells
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Role of mitochondrial calcium uniporter in regulating mitochondrial fission in the cerebral cortexes of living rats
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