- ￥2860
- LSM Bio
- 进口
- PAab09524
- 2025年07月16日
- ELISA,WB
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Werner syndrome, RecQ helicase-like
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
O95498
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
Werner syndrome, RecQ helicase-like
- 抗体英文名：
anti-WRN antibody,WRN antibody
- 抗体名：
anti-WRN 抗体,WRN 抗体
- 规格：
100μl
WRN抗体| WRN antibody
货号 PAab09524
蛋白别名 DKFZp686C2056 antibody, DNA helicase antibody, RecQ like type 3 antibody, Exonuclease WRN antibody, RecQ protein like 2 antibody, RECQ3 antibody, RECQL2 antibody, RECQL3 antibody, WRN
蛋白介绍
Multifunctional enzyme that has both magnesium and ATP- dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang. Has no nuclease activity towards single-stranded DNA or blunt-ended double- stranded DNA. Binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and Holliday junctions. May play an important role in the dissociation of joint DNA molecules that can arise as products of homologous recombination, at stalled replication forks or during DNA repair. Alleviates stalling of DNA polymerases at the site of DNA lesions. Important for genomic integrity. Plays a role in the formation of DNA replication focal centers; stably associates with foci elements generating binding sites for RP-A (By similarity). Plays a role in double-strand break repair after gamma-irradiation.
产品描述
anti-WRN antibody is a Rabbit Polyclonal antibody againstWRN..
建议稀释比例
WB:1:200-1:1000
IHC
Western blot
MCF-7 cells were subjected to SDS PAGE followed by western blot with PAab09524( WRN Antibody) at dilution of 1:300(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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