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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
vacuolar protein sorting 4 homolog B (S. cerevisiae)
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
O95498
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IF,IP
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
vacuolar protein sorting 4 homolog B (S. cerevisiae)
- 抗体英文名:
anti-VPS4B antibody,VPS4B antibody
- 抗体名:
anti-VPS4B 抗体,VPS4B 抗体
- 规格:
100μl
VPS4B抗体| VPS4B antibody
货号 PAab09446
蛋白别名 MIG1 antibody, Protein SKD1 antibody, SKD1 antibody, VPS4 2 antibody, VPS42 antibody, VPS4B
蛋白介绍
Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). VPS4A/B are required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).
产品描述
anti-VPS4B antibody is a Rabbit Polyclonal antibody againstVPS4B..
建议稀释比例
WB :1:500-1:5000;IP:1:500-1:5000;IF:1:10-1:100
IHC
Western blot
Y79 cells were subjected to SDS PAGE followed by western blot with PAab09446(VPS4B antibody) at dilution of 1:500(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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文献和实验
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