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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
ubiquitin specific peptidase 20
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC,IP
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
ubiquitin specific peptidase 20
- 抗体英文名:
anti-USP20 antibody,USP20 antibody
- 抗体名:
anti-USP20 抗体,USP20 抗体
- 规格:
100μl
USP20抗体| USP20 antibody
货号 PAab09317
蛋白别名 Deubiquitinating enzyme 20 antibody, hVDU2 antibody, KIAA1003 antibody, LSFR3A antibody, Ubiquitin thiolesterase 20 antibody, USP20 antibody, VDU2
蛋白介绍
Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
产品描述
anti-USP20 antibody is a Rabbit Polyclonal antibody againstUSP20..
建议稀释比例
WB : 1:200-1:2000;IHC:1:20-1:200;IP:1:200-1:2000
IHC
Immunohistochemistry of paraffin-embedded human kidney using PAab09317(USP20 antibody) at dilution of 1:50
Western blot
HepG2 cells were subjected to SDS PAGE followed by western blot with PAab09317(USP20 antibody) at dilution of 1:400(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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文献和实验
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