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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
solute carrier family 25 (mitochondrial carrier, brain), member 14
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
solute carrier family 25 (mitochondrial carrier, brain), member 14
- 抗体英文名:
anti-UCP5 antibody,UCP5 antibody
- 抗体名:
anti-UCP5 抗体,UCP5 抗体
- 规格:
100μl
UCP5抗体| UCP5 antibody
货号 PAab09230
蛋白别名 BMCP 1 antibody, BMCP1 antibody, SLC25A14 antibody, UCP 5 antibody, UCP5
蛋白介绍
UCP5, also known as BMCP1 (brain mitochondrial carrier protein-1), is a member of uncoupling proteins (UCPs) that catalyze proton leaks across the inner mitochondrial membrane, thus uncoupling fuel oxidation from ATP synthesis. UCPs are implicated in metabolic rate and adaptational thermoregulation. UCP5 is widely expressed with high abundance in brain and testis. Alternative splicing generates several isoforms of UCP5.
产品描述
anti-UCP5 antibody is a Rabbit Polyclonal antibody againstUCP5..
建议稀释比例
WB : 1:200-1:1000
IHC
Western blot
fetal human brain tissue were subjected to SDS PAGE followed by western blot with PAab09230( SLC25A14 Antibody) at dilution of 1:300(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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文献和实验Detection of Uncoupling Protein-2 (UCP2) As a Mitochondrial Modulator of Apoptosis
There is an increasing evidence that uncoupling protein-2 (UCP2), a recently identified molecular sensor and suppressor of mitochondrial reactive oxygen species (ROS), plays an important role in �regulating apoptosis in different cell systems
Cell Metab:北大邱义福团队发现「产热通道」介导的褐色脂肪产热新机制
肥胖已成为全球性的重大健康问题,在个体层面可以通过增加能量消耗来对抗肥胖。自 2009 年在成人中检测到代谢活跃的褐色/米色脂肪组织(BAT (brown adipose tissue) or beige fat)以来,科学家们一直在寻找增强褐色/米色脂肪产热从而增加能量消耗、抵抗肥胖的方法。 褐色脂肪组织线粒体富含解偶联蛋白 UCP1(uncoupling protein 1)。UCP1 能够提高线粒体内膜对质子的电导性,从而消耗质子梯度,将氧化磷酸化与 ATP 合成解偶联,把底物氧
【进展|热点】Nature:线粒体UCP2介导巨噬细胞吞噬功能---细胞吞噬新机制
生物通 报道:来自美国弗吉尼亚州立大学,斯坦福—伯纳姆医学研究所(Sanford-Burnham Medical Research Institute)发现了吞噬细胞线粒体膜蛋白Ucp2在细胞吞噬中的重要作用,这对于解释为什么吞噬细胞能接连消化多个凋亡细胞,而不影响其自身活动具有重要意义。这一研究成果公布在Nature杂志上。 成人每天能产生大量的凋亡细胞,比如大脑中的神经元,能存活下来的并不多,大部分都被吞噬细胞清除了,但是当吞噬细胞清楚死亡细胞的时候,它实质上使其细胞内容增加了一倍
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