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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
tripartite motif-containing 27
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC,IP
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
tripartite motif-containing 27
- 抗体英文名:
anti-TRIM27 antibody,TRIM27 antibody
- 抗体名:
anti-TRIM27 抗体,TRIM27 抗体
- 规格:
100μl
TRIM27抗体| TRIM27 antibody
货号 PAab08977
蛋白别名 Ret finger protein antibody, RFP antibody, RING finger protein 76 antibody, RNF76 antibody, TRIM27 antibody, tripartite motif containing 27 antibody, Zinc finger protein RFP
蛋白介绍
E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity; mediates the formation of 'Lys-48'-linked polyubiquitin chains; the function inhibits CD4 T- cell activation. Acts as a regulator of retrograde transport: together with MAGEL2, mediates the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASH1, leading to promote endosomal F-actin assembly (PubMed:23452853). Has a transcriptional repressor activity by cooperating with EPC1. Induces apoptosis by activating Jun N-terminal kinase and p38 kinase and also increases caspase-3-like activity independently of mitochondrial events. May function in male germ cell development. Has DNA-binding activity and preferentially bound to double- stranded DNA.
产品描述
anti-TRIM27 antibody is a Rabbit Polyclonal antibody againstTRIM27..
建议稀释比例
WB:1:500-1:2000;IP:1:500-1:5000;IHC:1:20-1:200;IF:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human lung cancer using PAab08977(TRIM27 antibody) at dilution of 1:100
Western blot
Jurkat cells were subjected to SDS PAGE followed by western blot with PAab08977(TRIM27 antibody) at dilution of 1:1000(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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