- ￥2860
- LSM Bio
- 进口
- PAab08967
- 2025年07月14日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
tripartite motif-containing 11
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
tripartite motif-containing 11
- 抗体英文名：
anti-TRIM11 antibody,TRIM11 antibody
- 抗体名：
anti-TRIM11 抗体,TRIM11 抗体
- 规格：
100μl
TRIM11抗体| TRIM11 antibody
货号 PAab08967
蛋白别名 BIA1 antibody, Protein BIA1 antibody, RING finger protein 92 antibody, RNF92 antibody, TRIM11 antibody, tripartite motif containing 11
蛋白介绍
E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway. Mediates MED15 ubiquitination leading to proteasomal degradation. May contribute to the innate restriction of retroviruses. Upon overexpression, reduces HIV-1 and murine leukemia virus infectivity, by suppressing viral gene expression. Antiviral activity depends on a functional E3 ubiquitin-protein ligase domain. May regulate TRIM5 turnover via the proteasome pathway, thus counteracting the TRIM5-mediated cross-species restriction of retroviral infection at early stages of the retroviral life cycle.
产品描述
anti-TRIM11 antibody is a Rabbit Polyclonal antibody againstTRIM11..
建议稀释比例
WB:1:200-1:1000;IHC:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human ovary tumor using PAab08967(TRIM11 antibody) at dilution of 1:100
Western blot
HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab08967(TRIM11 antibody) at dilution of 1:100(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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