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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
structure specific recognition protein 1
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
P67936
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC,IP
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
structure specific recognition protein 1
- 抗体英文名:
anti-SSRP1 antibody,SSRP1 antibody
- 抗体名:
anti-SSRP1 抗体,SSRP1 抗体
- 规格:
100μg
SSRP1抗体| SSRP1 antibody
货号 PAab08250
蛋白别名 FACT80
蛋白介绍
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II). Binds specifically to double-stranded DNA and at low levels to DNA modified by the antitumor agent cisplatin. May potentiate cisplatin-induced cell death by blocking replication and repair of modified DNA. Also acts as a transcriptional coactivator for p63/TP63.
产品描述
anti-SSRP1 antibody is a Rabbit Polyclonal antibody againstSSRP1..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human ovary tumor using PAab08250(SSRP1 antibody) at dilution of 1:100
Western blot
HeLa cells were subjected to SDS PAGE followed by western blot with PAab08250(SSRP1 antibody) at dilution of 1:500(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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