- ￥2860
- LSM Bio
- 进口
- PAab08132
- 2025年07月15日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
SP100 nuclear antigen
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
SP100 nuclear antigen
- 抗体英文名：
anti-SP100 antibody,SP100 antibody
- 抗体名：
anti-SP100 抗体,SP100 抗体
- 规格：
100μg
SP100抗体| SP100 antibody
货号 PAab08132
蛋白别名
蛋白介绍
Together with PML, this tumor suppressor is a major constituent of the PML bodies, a subnuclear organelle involved in a large number of physiological processes including cell growth, differentiation and apoptosis. Functions as a transcriptional coactivator of ETS1 and ETS2 according to PubMed:11909962. Under certain conditions, it may also act as a corepressor of ETS1 preventing its binding to DNA according to PubMed:15247905. Through the regulation of ETS1 it may play a role in angiogenesis, controlling endothelial cell motility and invasion. Through interaction with the MRN complex it may be involved in the regulation of telomeres lengthening. May also regulate TP53- mediated transcription and through CASP8AP2, regulate FAS-mediated apoptosis. Also plays a role in infection by viruses, including human cytomegalovirus and Epstein-Barr virus, through mechanisms that may involve chromatin and/or transcriptional regulation.
产品描述
anti-SP100 antibody is a Rabbit Polyclonal antibody againstSP100..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human ovary tumor using PAab08132(SP100antibody) at dilution of 1:50
Western blot
Jurkat cells were subjected to SDS PAGE followed by western blot with PAab08132(SP100 antibody) at dilution of 1:400(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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