- ￥2262
- LSM Bio
- 进口
- PAab08060
- 2025年07月15日
- ELISA,IF,WB,IHC,FC,IP
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
SNAP-associated protein
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,IF,WB,IHC,FC,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
SNAP-associated protein
- 抗体英文名：
anti-SNAPIN antibody,SNAPIN antibody
- 抗体名：
anti-SNAPIN 抗体,SNAPIN 抗体
- 规格：
100μg
SNAPIN抗体| SNAPIN antibody
货号 PAab08060
蛋白别名 BLOC1S7 antibody, SNAP25BP antibody, SNAPAP
蛋白介绍
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling. May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release through its ability to potentiate the interaction of synaptotagmin with the SNAREs and the plasma- membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells (PubMed:17182842, PubMed:18167355). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167).
产品描述
anti-SNAPIN antibody is a Rabbit Polyclonal antibody againstSNAPIN..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human testis tissue slide using PAab08060( SNAPIN Antibody) at dilution of 1:200
Western blot
rat brain tissue were subjected to SDS PAGE followed by western blot with PAab08060( SNAPIN Antibody) at dilution of 1:200(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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