- ￥2262
- LSM Bio
- 进口
- PAab08052
- 2025年07月16日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
snail homolog 2 (Drosophila)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
snail homolog 2 (Drosophila)
- 抗体英文名：
anti-SNAI2 antibody,SNAI2 antibody
- 抗体名：
anti-SNAI2 抗体,SNAI2 抗体
- 规格：
100μg
SNAI2抗体| SNAI2 antibody
货号 PAab08052
蛋白别名 SLUG antibody, SLUGH
蛋白介绍
Transcriptional repressor that modulates both activator- dependent and basal transcription. Involved in the generation and migration of neural crest cells. Plays a role in mediating RAF1- induced transcriptional repression of the TJ protein, occludin (OCLN) and subsequent oncogenic transformation of epithelial cells (By similarity). Represses BRCA2 expression by binding to its E2- box-containing silencer and recruiting CTBP1 and HDAC1 in breast cells. In epidermal keratinocytes, binds to the E-box in ITGA3 promoter and represses its transcription. Involved in the regulation of ITGB1 and ITGB4 expression and cell adhesion and proliferation in epidermal keratinocytes. Binds to E-box2 domain of BSG and activates its expression during TGFB1-induced epithelial-mesenchymal transition (EMT) in hepatocytes. Represses E-Cadherin/CDH1 transcription via E-box elements. Involved in osteoblast maturation. Binds to RUNX2 and SOC9 promoters and may act as a positive and negative transcription regulator, respectively, in osteoblasts. Binds to CXCL12 promoter via E-box regions in mesenchymal stem cells and osteoblasts. Plays an essential role in TWIST1-induced EMT and its ability to promote invasion and metastasis.
产品描述
anti-SNAI2 antibody is a Rabbit Polyclonal antibody againstSNAI2..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human kidney using PAab08052(SNAI2 antibody) at dilution of 1:200
Western blot
mouse pancreas tissue were subjected to SDS PAGE followed by western blot with PAab08052(SNAI2 antibody) at dilution of 1:300(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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