- ￥2262
- LSM Bio
- 进口
- PAab07898
- 2025年07月16日
- ELISA,IHC,WB,IP,IF
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
S-phase kinase-associated protein 2 (p45)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,IHC,WB,IP,IF
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
S-phase kinase-associated protein 2 (p45)
- 抗体英文名：
anti-SKP2 antibody,SKP2 antibody
- 抗体名：
anti-SKP2 抗体,SKP2 抗体
- 规格：
100μg
SKP2抗体| SKP2 antibody
货号 PAab07898
蛋白别名 FBXL1
蛋白介绍
Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UBP43, and probably MYC, TOB1 and TAL1. Degradation of TAL1 also requires STUB1. Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2. Promotes ubiquitination and destruction of CDH1 in a CK1-Dependent Manner, thereby regulating cell migration.
产品描述
anti-SKP2 antibody is a Rabbit Polyclonal antibody againstSKP2..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using PAab07898( SKP2 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Western blot
HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab07898( SKP2 Antibody) at dilution of 1:600(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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