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- 技术资料
- 免疫原:
ring finger protein 1
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
P67936
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
ring finger protein 1
- 抗体英文名:
anti-RING1 antibody,RING1 antibody
- 抗体名:
anti-RING1 抗体,RING1 抗体
- 规格:
100μg
RING1抗体| RING1 antibody
货号 PAab07308
蛋白别名 RNF1
蛋白介绍
Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity.
产品描述
anti-RING1 antibody is a Rabbit Polyclonal antibody againstRING1..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human prostate cancer using PAab07308(RING1 antibody) at dilution of 1:50
Western blot
mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with PAab07308(RING1 antibody) at dilution of 1:500(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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