- ￥2262
- LSM Bio
- 进口
- PAab07378
- 2025年07月15日
- ELISA,WB,IHC,IF,IP
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Rho-associated, coiled-coil containing protein kinase 2
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC,IF,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
Rho-associated, coiled-coil containing protein kinase 2
- 抗体英文名：
anti-ROCK2 antibody,ROCK2 antibody
- 抗体名：
anti-ROCK2 抗体,ROCK2 抗体
- 规格：
100μg
ROCK2抗体| ROCK2 antibody
货号 PAab07378
蛋白别名 KIAA0619
蛋白介绍
Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. Plays an important role in generating the circadian rhythm of the aortic myofilament Ca(2+) sensitivity and vascular contractility by modulating the myosin light chain phosphorylation.
产品描述
anti-ROCK2 antibody is a Rabbit Polyclonal antibody againstROCK2..
建议稀释比例
WB:1:1000-1:10000 IP:1:200-1:2000 IHC:1:20-1:200 IF:1:10-1:100
IHC
Immunohistochemistry of paraffin-embedded human liver using PAab07378(ROCK2 antibody) at dilution of 1:100
Western blot
HT-1080 cells were subjected to SDS PAGE followed by western blot with PAab07378(ROCK2 antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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