- ￥2262
- LSM Bio
- 进口
- PAab06067
- 2025年07月16日
- ELISA,IHC,IF,WB
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9WVH4
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,IHC,IF,WB
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
- 抗体英文名：
anti-P21;CDKN1A antibody,P21;CDKN1A antibody
- 抗体名：
anti-P21;CDKN1A 抗体,P21;CDKN1A 抗体
- 规格：
100μl
P21;CDKN1A抗体| P21;CDKN1A antibody
货号 PAab06067
蛋白别名 CAP20 antibody, CDK interacting protein 1 antibody, CDKN1 antibody, CDKN1A antibody, CIP1 antibody, MDA 6 antibody, MDA6 antibody, P21 antibody, p21CIP1 antibody, PIC1 antibody, SDI1 antibody, WAF1
蛋白介绍
CDKN1A (p21, CIP1, WAF1) is a cyclin-dependent kinase inhibitor. CDKN1A binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at the G1 phase. The expression of CDKN1A is induced by wild-type but not mutant p53 protein, through which CDKN1A mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. CDKN1A can interact with proliferating cell nuclear antigen (PCNA), and plays a regulatory role in S phase DNA replication and DNA damage repair. CDKN1A was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Two alternatively spliced variants, which encode an identical protein, have been reported.
产品描述
anti-P21;CDKN1A antibody is a Rabbit Polyclonal antibody againstP21;CDKN1A..
建议稀释比例
WB:1:500-1:5000;IP:1:200-1:1000;IHC:1:50-1:500;IF:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human kidney using PAab06067(P21 antibody) at dilution of 1:50
Western blot
HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab06067(P21 antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!) <"">
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文献和实验
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