- ￥2262
- LSM Bio
- 进口
- PAab05801
- 2025年07月16日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
nephroblastoma overexpressed gene
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9WVH4
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
nephroblastoma overexpressed gene
- 抗体英文名：
anti-NOV antibody,NOV antibody
- 抗体名：
anti-NOV 抗体,NOV 抗体
- 规格：
100μl
NOV抗体| NOV antibody
货号 PAab05801
蛋白别名 CCN3 antibody, IGFBP9 antibody, NOVH
蛋白介绍
Immediate-early protein playing a role in various cellular processes including proliferation, adhesion, migration, differentiation and survival (PubMed:15181016, PubMed:15611078, PubMed:12695522, PubMed:21344378, PubMed:12050162). Acts by binding to integrins or membrane receptors such as NOTCH1 (PubMed:12695522, PubMed:21344378, PubMed:15611078). Essential regulator of hematopoietic stem and progenitor cell function (PubMed:17463287). Inhibits myogenic differentiation through the activation of Notch-signaling pathway (PubMed:12050162). Inhibits vascular smooth muscle cells proliferation by increasing expression of cell-cycle regulators such as CDKN2B or CDKN1A independently of TGFB1 signaling (PubMed:20139355). Ligand of integrins ITGAV:ITGB3 and ITGA5:ITGB1, acts directly upon endothelial cells to stimulate pro-angiogenic activities and induces angiogenesis. In endothelial cells, supports cell adhesion, induces directed cell migration (chemotaxis) and promotes cell survival (PubMed:12695522). Plays also a role in cutaneous wound healing acting as integrin receptor ligand. Supports skin fibroblast adhesion through ITGA5:ITGB1 and ITGA6:ITGB1 and induces fibroblast chemotaxis through ITGAV:ITGB5. Seems to enhance bFGF-induced DNA synthesis in fibroblasts (PubMed:15611078). Involved in bone regeneration as a negative regulator (By similarity). Enhances the articular chondrocytic phenotype, whereas it repressed the one representing endochondral ossification (PubMed:21871891). Impairs pancreatic beta-cell function, inhibits beta-cell proliferation and insulin secretion (By similarity). Plays a role as negative regulator of endothelial pro-inflammatory activation reducing monocyte adhesion, its anti- inflammatory effects occur secondary to the inhibition of NF- kappaB signaling pathway (PubMed:21063504). Contributes to the control and coordination of inflammatory processes in atherosclerosis (By similarity). Attenuates inflammatory pain through regulation of IL1B- and TNF-induced MMP9, MMP2 and CCL2 expression. Inhibits MMP9 expression through ITGB1 engagement (PubMed:21871891).
产品描述
anti-NOV antibody is a Rabbit Polyclonal antibody againstNOV..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human nephroblastoma using PAab05801(NOV antibody) at dilution of 1:50
Western blot
mouse liver tissue were subjected to SDS PAGE followed by western blot with PAab05801(NOV antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!) <"">
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文献和实验纳米颗粒外泌体的制备及体内注射 ACS Nano. 2017 Nov 28;11(11):10883-10893. 图 9 用金纳米颗粒和 PKH26 对外泌体进行双标记 ACS Nano. 2017 Nov 28;11(11):10883-10893. 四、用近红外（NIR）荧光探针进行标记： 这是一种使用两亲性探针对 NIR 荧光标记的外泌体进行内源性检测的方法，无需对外泌体进行免疫标记或合成或色谱处理。由于 NIR 波长的荧光探针能穿透体内组织，从而提供了从细胞直接转换到体内
silencing of an endogenous gene by systemic administration of modified siRNAs Soutschek J. et al . Nature 432 , 173 - 178 (11 Nov 2004) Processing of primary microRNAs by the Microprocessor complex
你不得不知道的 ImageJ 图像处理工具——Plot Profile
选框，选中白色箭头所指的地方即可。我们可以发现在白色箭头画一矩形选框，分别对 R 红色通道，G 绿色通道进行 Plot Profile，分别得到矩形范围内荧光强度变化（上面为红色荧光通道，下面为绿色荧光通道）:参考文献Nuclear DNA helicase II is recruited to IFN-alpha-activated transcription sites at PML nuclear bodies. Fuchsová B, Novák P, Kafková J, Hozák P
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