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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
neural precursor cell expressed, developmentally down-regulated 4-like
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9WVH4
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
neural precursor cell expressed, developmentally down-regulated 4-like
- 抗体英文名:
anti-NEDD4L antibody,NEDD4L antibody
- 抗体名:
anti-NEDD4L 抗体,NEDD4L 抗体
- 规格:
100μl
NEDD4L抗体| NEDD4L antibody
货号 PAab05646
蛋白别名 KIAA0439 antibody, NEDL3
蛋白介绍
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK1 and TNK2. Ubiquitinates BRAT1 and this ubiquitination is enhanced in the presence of NDFIP1 (PubMed:25631046). Plays a role in dendrite formation by melanocytes (PubMed:23999003).
产品描述
anti-NEDD4L antibody is a Rabbit Polyclonal antibody againstNEDD4L..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human prostate cancer using PAab05646(NEDD4L antibody) at dilution of 1:100
Western blot
K-562 cells were subjected to SDS PAGE followed by western blot with PAab05646(NEDD4L antibody) at dilution of 1:500(本抗体仅供体外科研用途,不可用于临床诊断!) <"">
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