- ￥2650
- LSM Bio
- 进口
- PAab04848
- 2025年07月15日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
low density lipoprotein receptor-related protein 5
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P15248
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
low density lipoprotein receptor-related protein 5
- 抗体英文名：
anti-LRP5 antibody,LRP5 antibody
- 抗体名：
anti-LRP5 抗体,LRP5 抗体
- 规格：
100μg
LRP5抗体| LRP5 antibody
货号 PAab04848
蛋白别名 LR3 antibody, LRP7
蛋白介绍
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor- ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. Plays a role in norrin (NDP) signal transduction (PubMed:27228167). The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta- catenin. Appears be required for postnatal control of vascular regression in the eye (By similarity). Required for posterior patterning of the epiblast during gastrulation (By similarity).
产品描述
anti-LRP5 antibody is a Rabbit Polyclonal antibody againstLRP5..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using PAab04848( LRP5 Antibody) at dilution of 1:50
Western blot
HeLa cells were subjected to SDS PAGE followed by western blot with PAab04848( LRP5 Antibody) at dilution of 1:600(本抗体仅供体外科研用途，不可用于临床诊断!) <"">
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