- ￥2262
- LSM Bio
- 进口
- PAab03833
- 2026年03月23日
- ELISA,WB,IHC,FC,IP
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P15248
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC,FC,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
- 抗体英文名：
anti-HER2/ErbB2 antibody,HER2/ErbB2 antibody
- 抗体名：
anti-HER2/ErbB2 抗体,HER2/ErbB2 抗体
- 规格：
100μg
HER2/ErbB2抗体| HER2/ErbB2 antibody
货号 PAab03833
蛋白别名 CD340 antibody, ERBB2 antibody, HER 2 antibody, HER 2/neu antibody, HER2 antibody, MLN 19 antibody, MLN19 antibody, NEU antibody, NGL antibody, p185 antibody, p185erbB2 antibody, Proto oncogene c ErbB 2 antibody, Proto oncogene Neu antibody, TKR1
蛋白介绍
HER2, also known as ErbB2 and Neu, is a 185-kDa transmembrane glycoprotein that is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. It has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase- mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of HER2 have been reported in numerous cancers, including breast and ovarian tumors. HER2 is a therapeutic target for the treatment of breast cancer and other carcinomas. This antibody raised against a synthesized peptide corresponding to 1237-1255aa of human HER2 recognizes the 185-kDa full-length glycosylated form and other lower molecular-mass forms of HER2, including the truncated form.
产品描述
anti-HER2/ErbB2 antibody is a Rabbit Polyclonal antibody againstHER2/ErbB2..
建议稀释比例
WB : 1:1000-1:10000 IP : 1:200-1:2000 IHC : 1:50-1:200
IHC
Immunohistochemistry of paraffin-embedded human breast cancer using PAab03833(ERBB2 antibody) at dilution of 1:50
Western blot
HeLa cells were subjected to SDS PAGE followed by western blot with PAab03833(ERBB2 antibody) at dilution of 1:300(本抗体仅供体外科研用途，不可用于临床诊断!) <"">
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祝贺〖上海雅裕 〗成为 Signalway Antibody 品牌 (SAB) 的独家总代理。 促销【 ABCD 】细则如下： 【 A 】 买两支 SAB 抗体免费获得 8G 优盘 活动时间：即日起，至 2011 年
物-人表皮生长因子受体-2（HER2，也称 Neu 或 ERBB2）为例，临床上 Her2 的检测多采用免疫组织化学法检测其表达水平，也是决定要不要使用标靶治疗的依据之一。GTX100509 HER2/ERBB2 抗体使用 2 个不同来源的抗体进行比较（如下），确认有一致性的染色图谱，而 GTX100509 灵敏度甚至比其他厂家来的更高。3. 免疫捕获及质谱分析官兵抓强盗，敌友谁知道，预知此名号，捉拿验证号。将免疫捕获的目标蛋白进行质谱分析，可确认捕获的蛋白身份是否为目标蛋白，以此确认抗体是否辨识到对的蛋白
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