- ￥2062
- LSM Bio
- 进口
- PAab01444
- 2025年07月15日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD22 molecule
- 亚型：
IgG1
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Monoclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Mouse
- 目录编号：
Q9GZT9
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
CD22
- 抗体英文名：
anti-CD22 antibody,CD22 antibody
- 抗体名：
anti-CD22 抗体,CD22 抗体
- 规格：
100μg
CD22抗体| CD22 antibody
货号 PAab01444
蛋白别名 SIGLEC2
蛋白介绍
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
产品描述
anti-CD22 antibody is a Mouse Monoclonal antibody againstCD22..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using PAab01444( CD22 Antibody) at dilution of 1:400 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Western blot
Raji cells were subjected to SDS PAGE followed by western blot with PAab01444(CD22 antibody) at dilution of 1:1500(本抗体仅供体外科研用途，不可用于临床诊断!)
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文献和实验CD22 分子 CD22 常用单克隆抗体或代号： B3,HD39,Leu14,SHCL- 1,HC2 (BL- CAM) 主要表达细胞： B [B] 分子质量(kDa)和结构： gp130/140,髓鞘(磷)脂相关蛋白类似物(MAG)(IgSF) 功 能： 与CD45RO、CD75结合,B细胞粘附到M、红细胞,介导B- B、B- T细胞相互作用 CD22 Aka B
Anti-CD22 Onconase: Preparation and Characterization
Antibodies can be conjugated to effector molecules to derive targeted therapeutics with properties such as cell-specific cytotoxicity. The murine anti-CD22 antibody RFB4 linked to a member of the ribonuclease A superfamily, Onconase (Onc
CD40 ／ CD22 白细胞分化抗原及其功能 CD40 属于TNFR-SF，胞膜外区有4个富含牛胱氨酸重复序列(图6―2)，表达于APC细胞，以及某些上皮细胞、内皮细胞、成纤维细胞、淋巴样并指细胞、FDC以及活化的单核细胞。浆细胞不表达CD40分子。 CD40结合CD40L(CDl54)，胞质区Thr234是CD40介导信号转导关键的氨基酸残基。CD40-CD40L相互作用是B细胞活化中第二信号的主要来源，而且对于T
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