- ￥2062
- LSM Bio
- 进口
- PAab00355
- 2025年07月12日
- ELISA,IHC,WB
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
alpha-methylacyl-CoA racemase
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9GZT9
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,IHC,WB
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
AMACR/p504S
- 抗体英文名：
anti-AMACR/p504S antibody,AMACR/p504S antibody
- 抗体名：
anti-AMACR/p504S 抗体,AMACR/p504S 抗体
- 规格：
100μg
AMACR/p504S抗体| AMACR/p504S antibody
货号 PAab00355
蛋白别名 2 methylacyl CoA racemase antibody, alpha methylacyl CoA racemase antibody, AMACR antibody, CBAS4 antibody, p504S antibody, RACE
蛋白介绍
AMACR(Alpha-methylacyl-CoA racemase) belongs to the CaiB/BaiF CoA-transferase family. It is a mitochondrial and peroxisomal enzyme that catalyzes the conversion of 2R stereoisomers of phytanic and pristanic acid to their S counterparts. AMACR has previously been shown to be a highly sensitive marker for colorectal and clinically localized prostate cancer (PCa). However, AMACR expression is down-regulated at the transcript and protein level in hormone-refractory metastatic PCa, suggesting a hormone-dependent expression of AMACR(PMID:12213712). It has 3 isoforms produced by alternative splicing ang it can form a a dimer of 70-75 kDa(PMID:21812041). Defects in AMACR are the cause of alpha-methylacyl-CoA racemase deficiency (AMACRD) and congenital bile acid synthesis defect type 4 (CBAS4).
产品描述
anti-AMACR/p504S antibody is a Rabbit Polyclonal antibody againstAMACR/p504S..
建议稀释比例
WB :1:500-1:5000;IHC:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human prostate cancer using PAab00355(p50S,AMACR antibody) at dilution of 1:50
Western blot
Recombinant AMACR protein were subjected to SDS PAGE followed by western blot with PAab00355( AMACR Antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!)
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文献和实验; stippled line, control staining without primary antibody. Screening for upregulation of target genes in human cell lines. We delivered millions of TFZF s into the human squamous carcinoma cell line A431 using a retroviral vector, pMX-IRES-GFP15 (Fig
Phage‐Based Expression Cloning to Identify Interacting Proteins
, W., Sellers, W.R., DeCaprio, J.A., Ajchenbaum, F., Fuchs, C.S., Chittenden, T., Li, Y., Farnham, P.J., Blanar, M.A., Livingston, D.M., and Flemington, E.K. 1992. Expression cloning of a cDNA encoding a retinoblastoma‐binding protein with E2F
[资源] 所有的看家基因(housekeeping genes)列表+引物设计服务
(protein disulfide isomerase; thyroid hormone binding protein p55) (P4HB), mRNA 2719 NM_004584 Homo sapiens RAD9 homolog (S. pombe) (RAD9), mRNA 860 NM_004952 Homo sapiens ephrin-A3 (EFNA3), mRNA 505 NM_004308 Homo sapiens Rho GTPase activating
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