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文献和实验Free-Flow Electrophoresis of the Human Urinary Proteome
Prefractionation of complex protein samples prior to mass spectrometry provides a method for the isolation of low-abundance proteins into specific fractions thereby enabling their identification. Free-flow electrophoresis in the isoelectric
Use of Animal Models to Understand Human Muscular Dystrophy
actin in the cytoskeleton with laminin in the extra cellular matrix, have been shown to result in several human MD syndromes (3 ). Defects in α-, β-, γ-, and δ-sarcoglycans, which are components of the DGC, are associated with limb-girdle MDs (LGMD) 2D, E, C, and F
bioinformatics. This leads to an increased emphasis on larger scale, faster, and more efficient methods for detecting protein biomarkers in human tissues, cells, and biofluids. Most current proteomic methodologies for biomarker discovery, however, are not highly
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