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文献和实验Mica Functionalization for Imaging of DNA and Protein-DNA Complexes with Atomic Force Microscopy
Surface preparation is a key step for reliable and reproducible imaging of DNA and protein-DNA complexes with atomic force microscopy (AFM). This article describes the approaches for chemical functionalization of the mica surface
Atomic Force Microscopy of DNA and Protein-DNA Complexes Using Functionalized Mica Substrates
Atomic force microscopy (AFM; also called scanning force microscopy [SFM]) is a rather novel technique that offers unique advantages in the potential for the very high resolution of DNA and small ligands in the absence of stains, shadows
Immortalised cultured cells are powerful tools to assess the function of ectopically expressed proteins. However, it must be ensured that the protein of interest is functional in the host system and display native behaviour. In particular
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