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文献和实验The CRE Luc Mouse Model for Bioimaging Ligand Activation of G Protein-Coupled Receptors
from a luciferase reporter have been used extensively in vitro with high-throughput screens (HTS) of large chemical compound libraries. We have generated a transgenic mouse model (CRE luc) with a luciferase reporter under the control of a synthetic promoter
Using AutoDock for Ligand‐Receptor Docking
up and analyze ligand?protein docking calculations using AutoDock and the graphical user interface, AutoDockTools (ADT). The AutoDock scoring function is a subset of the AMBER force field that treats molecules using the United Atom model. The unit uses an X?ray
survival advantage for these cells (2) . Tumors with developed resistance to apoptosis can survive despite an active immune system. The Fas receptor (APO-1 or CD95) and its ligand play a key role in the initiation of one apoptotic pathway in malignant
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