CD156c 多克隆抗体

Western Blot（WB）已验证样本:Hela,A549,SKOV3,Mouse spleen,Mouse lung,Mouse brain,Rat brain

WB 1:500-1:1000

Polyclonal

IgG

KLH conjugated Synthetic peptide corresponding to Mouse ADAM10

CD156c

A disintegrin and metalloprotease domain 10;A disintegrin and metalloproteinase domain 10;AD 10;AD10;AD18;ADA10;ADAM 10;ADAM metallopeptidase domain 10;ADAM10;CD 156c;CD156c;CD156c antigen;CDw156;disintegrin and metalloproteinase domain containing protein 10;Disintegrin and metalloproteinase domain-containing protein 10;HsT 18717;HsT18717;Kuz;Kuzbanian;Kuzbanian protein homolog;Kuzbanian;Drosophila;homolog of;MADM;Mammalian disintegrin metalloprotease;Mammalian disintegrin-metalloprotease;RAK抗体

O14672,O35598,Q10743

84kDa

95kDa

Cell membrane. Endomembrane system. Is localized in the plasma membrane but is predominantly expressed in the Golgi apparatus and in released membrane vesicles derived likely from the Golgi.

210 μg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Affinity purification

Cancer; Cell Biology; Signal Transduction

Unconjugated

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP).