NRG1 多克隆抗体

Western Blot（WB）已验证样本:A549

WB 1:500-1:2000

Polyclonal

IgG

Synthetic peptide of human NRG1

NRG1

Acetylcholine receptor-inducing activity;Acetylcholine receptor-inducing activity;CHICK;homolog of;ARIA;Breast cancer cell differentiation factor p45;GGF;GGF2;Glial growth factor;Heregulin;heregulin;alpha (45kD;ERBB2 p185-activator);HGL;HRG;HRG1;HRGA;MST131;NDF;Neu differentiation factor;Neuregulin 1;neuregulin 1 type IV beta 1a;neuregulin 1 type IV beta 3;Neuregulin-1;NRG 1;nrg1;NRG1-IT2;NRG1;OTTHUMP00000225398;OTTHUMP00000225419;OTTHUMP00000225420;OTTHUMP00000225421;OTTHUMP00000225422;OTTHUMP00000225477;OTTHUMP00000225545;OTTHUMP00000230603;OTTHUMP00000230605;pro-neuregulin-1;membrane-bound isoform;Pro-NRG1;ProNRG1;Sensory and motor neuron-derived factor;SMDF抗体

Q02297

70kDa

Secreted; Cell membrane. Does not seem to be active; Membrane. May possess an internal uncleaved signal sequence; Nucleus. May be nuclear and Secreted. Has a signal peptide.

0.8 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Neuroscience; Signal Transduction

Unconjugated

The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD).