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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
Human Phosphatidylinositol 3-kinase regulatory subunit beta(PIK3R2) ELISA kit
- 供应商:
广州威佳科技有限公司
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文献和实验Introduction of human 14-3-3 proteins
with several tyrosine-phosphorylated proteins and phosphatidylinositol 3-kinase (PI3-K)in T cells.We report here the identification of the 120-kDa 14-3-3tau-binding phosphoprotein present in activated T cell lysates as Cbl,a protooncogene product of unknown function
. The activity of these targets leads to survival, cytoskeletal rearrangement and transformation. GSK3 β lycogen synthase kinase-3; NF-κB, nuclear factor of κB; PDK1/2, 3-phosphoinositide-dependent protein kinase 1/2.
Two-hybrid analysis of genetic regulatory networks
but absent in the non-interacting Cdks; inspection of an alignment of the Cdk protein sequences suggested residues that may be important for specific interactions with certain Cdis. Second, Cdi3, Drosophila Cyclin D, interacted much more strongly with human
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