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文献和实验High-Performance Liquid Chromatography Analysis of CYP2C8-Catalyzed Paclitaxel 6-Hydroxylation
. A reverse-phase, high-performance liquid chromatographic assay is described for the analysis of paclitaxel 6α-hydroxylation catalyzed by human liver microsomes or cDNA-expressed P450 enzyme CYP2C8. Analytical separations are achieved using a C18 column
中科院高福院士课题组 2020 年发表了哪些重要的研究成果?
抗体的主要靶标。2020 年 3 月 11 日,高福院士联合逯光文在 Cell Host & Microbe 发文:Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody。该研究报告了狂犬病毒 RABV-G 的晶体结构,分别在〜pH-8.0 时以游离形式和在〜pH-6.5 时与中和
High-Performance Liquid Chromatographic Analysis of CYP2CSCatalyzed Paclitaxel 6-Hydroxylation
CYP2C8 is a major CYP2C protein expressed in human liver 1 –4 . Considerable interindividual differences (-20-fold) have been observed in hepatic CYP2C8 content (5 ) and a blmodal dlstrlbutlon in CYP2C8 protein amounts m a panel of human
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